8/11/2023 0 Comments Ideopathic hupersomnia hypnogram![]() ![]() One current hypothesis is that in a few cases, there appears to be overproduction of a small molecule present in cerebrospinal fluid that acts like a sleeping pill or anesthetic. It is possible that there may be multiple causes, each of which applies to a subset of the IH population. IH is a disorder of the brain and central nervous system whose cause is not known. To create a care plan for emergencies or upcoming planned anesthesia or hospitalization, see our Anesthesia, Hospitalization and Emergency Planning page. IH symptoms and the medications used to treat them may lead to difficulties with anesthesia and hospital care. In contrast to the short and generally refreshing daytime naps observed in narcolepsy type 1, those naps in IH patients can be very long-on the scale of hours-and are usually unrefreshing. Sleep is usually described as “deep,” and arousal from sleep is usually difficult, often requiring multiple alarm clocks and morning rituals to ensure that patients arise for school or work. Symptoms may spontaneously remit in 10-15% of patients (read more HERE). Symptom intensity often varies (between weeks, months, or years) and can worsen just prior to menses in women. Symptoms often first appear in the mid-to-late teens or early twenties, although they can begin in childhood or at a later age. Even with medication, patients may struggle with these activities. If an effective medication to control symptoms cannot be found, it can be extremely difficult for people with IH to hold down jobs, remain in school, maintain marriages, and fully engage with their family and friends. The disorder is chronic, and the symptoms can be relentless. Many people with IH sleep more than 11 hours out of every 24. Thinking clearly and carrying out even basic tasks can be difficult. Sleep seems to leave a mental fogginess, which can remain throughout the few hours that people with IH can remain awake. While people without sleep disorders may wake up and briefly want to return to sleep, in people with idiopathic hypersomnia, this sleep-to-wake transition is much more difficult and prolonged. Additional symptoms commonly include unrefreshing or non-restorative sleep, and severe sleep inertia/ sleep drunkenness, which is extreme difficulty awakening from sleep, accompanied by feelings of grogginess and disorientation upon awakening. The main symptom of IH is excessive daytime sleepiness despite adequate, or more typically, long sleep amounts (e.g., more than 10-11 hours per night). What Are the Symptoms of Idiopathic Hypersomnia? International Patient Registry – Join or Update Your Data.Guides for Working With People With Hypersomnias.International Healthcare Provider Directory.Treatment of central disorders of hypersomnolence: An American Academy of Sleep Medicine clinical practice guideline. Hypersomnia evaluation, treatment and social and economic aspects. Idiopathic hypersomnia and hypersomnolence disorder: A systematic review of the literature. Efficacy and safety of modafinil in patients with idiopathic hypersomnia without long sleep time: A multicenter, randomized, double-blind, placebo-controlled, parallel-group comparison study. Practice parameters for clinical use of the multiple sleep latency test and the maintenance of wakefulness test. Safety and efficacy of lower-sodium oxybate in adults with idiopathic hypersomnia: A phase 3, placebo-controlled, double-blind, randomized withdrawal study. Idiopathic hypersomnia and other hypersomnia syndromes. Genetic and Rare Diseases Information Center. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |